The decoction contains 14 herbs, namely, Radix Rehmanniae ( Rehmannia glutinosa Libosch, root), Cornu Bubali ( Bubalus bubalis Linnaeus, horns), Rhizoma Coptidis ( Coptis chinensis Franch, root and rhizome), Fructus Gardeniae ( Gardenia jasminoides Ellis, fruit), Radix Platycodonis ( Platycodon grandiflorum (Jacq.) A. Qingwen Baidu Decoction (QBD), a famous traditional Chinese medicine prescription (TCMP) with heat-clearing, fire-purging, blood-cooling and detoxifying efficacies, has been widely used to treat epidemic encephalitis B, epidemic hemorrhagic fever, sepsis and many other inflammatory diseases (Zheng et al., 2017 Yu et al., 2014 Shen et al., 2012).
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